CAS No.: 147817-50-3
1'-(4-(1-(4-Fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4'-piperidine] Catalog No. CSN16114
Synonyms: Lu 28-179
Siramesine is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Cesen MH, Repnik U, et al. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Cell Death Dis. 2013 Oct 3;4:e818.
- [2] Spirkoski J, Melo FR, et al. Mast cell apoptosis induced by siramesine, a sigma-2 receptor agonist. Biochem Pharmacol. 2012 Dec 15;84(12):1671-80.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 147817-50-3 | 储存条件 |
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| 分子式 | C30H31FN2O | 运输 | 蓝冰 | |
| 分子量 | 454.58 | 别名 | Lu 28-179 |
